Male infertility: the role of hormonal evaluation in guiding therapy

Ie-Wen Sim, Rob McLachlan



Although endocrine causes of male infertility are uncommon, reproductive hormonal evaluation is an integral component of the evaluation of male factor infertility. This article discusses the role of hormonal evaluation and demonstrates its capacity to influence therapeutic choices.

Key Points

  • As part of the evaluation of the infertile couple, male factor infertility needs to be considered.
  • In addition to testicular examination and semen analysis, reproductive hormone testing is an important component of the diagnostic workup of infertile men.
  • Although endocrine causes account for a small proportion of male infertility, they are often remediable by specific therapy.
  • Testosterone therapy should not be commenced in men with fertility aspirations due to its contraceptive effects.