Managing premature menopause: what is the best approach?

Amanda J Vincent



Premature menopause presents a diagnostic and management challenge to clinicians. A multidisciplinary approach is recommended, with management directed at symptom control, screening, prevention and management of long-term complications, and provision of psychological support and information about the condition.

Key Points

  • The diagnosis of premature menopause should be considered in young women presenting with menstrual disturbance/amenorrhoea. The diagnosis should be conveyed in a sensitive manner.
  • Women with premature menopause experience significant psychological distress.
  • Hormone replacement therapy (unless contraindicated) should be given to women with premature menopause until 51 years of age.
  • Long-term consequences of premature menopause, such as osteoporosis, need to be screened for and managed.
  • Provision of information to affected women about premature menopause is essential.